What is a human phenotype?

Phenotype refers to an individual’s observable traits, such as height, eye color and blood type. A person’s phenotype is determined by both their genomic makeup (genotype) and environmental factors.

What are HPO terms?

The Human Phenotype Ontology (HPO) provides a standardized vocabulary of phenotypic abnormalities encountered in human disease. Each term in the HPO describes a phenotypic abnormality, such as Atrial septal defect. The HPO is currently being developed using the medical literature, Orphanet, DECIPHER, and OMIM.

What are 3 examples of phenotype?

In humans, phenotype examples include earwax type, height, blood type, eye color, freckles, and hair color. And phenotypes aren’t just physical traits. Behavior is also considered a phenotype.

What phenotypic variations can be observed in humans?

Phenotypic variation, then, is the variability in phenotypes that exists in a population. For example, people come in all shapes and sizes: height, weight, and body shape are phenotypes that vary. Hair, eye color, and the ability to roll your tongue are variable phenotypes, too.

What is HPO in body?

The Human Phenotype Ontology (HPO)—a standardized vocabulary of phenotypic abnormalities associated with 7000+ diseases—is used by thousands of researchers, clinicians, informaticians and electronic health record systems around the world.

What is phenotype in psychology?

n. the observable characteristics of an individual, such as morphological or biochemical features and the presence or absence of a particular disease or condition.

What are the types of phenotypes?

Examples of phenotypes include height, wing length, and hair color. Phenotypes also include observable characteristics that can be measured in the laboratory, such as levels of hormones or blood cells.

Why are there so many phenotypes in humans?

Human features like height, eye color, and hair color come in lots of slightly different forms because they are controlled by many genes, each of which contributes some amount to the overall phenotype.

Why is there so much phenotypic variation in humans?

Phenotypic variation in humans is a direct consequence of genetic variation, which acts in conjunction with environmental and behavioral factors to produce phenotypic diversity. Genetic variants are classified by two basic criteria: their genetic composition and their frequency in the population.

What is human genotype?

Genotype, very simply, is the version of a DNA sequence that an individual has. There’s a large amount of DNA that we all have in common–of course, that’s why we’re all humans–but there’s also a large amount of variation in sequence among individuals.

How many phenotypes are possible?

The genetic locus, ABO locus encodes for the ABO blood group antigens. It has 3 allelic forms – A form, B form and O form. A fetus receives one of these three alleles from each of its parents. This produces four possible phenotypes (blood types) and six possible genotypes.

What is HPO framework?

HPO Center – The High Performance Organization (HPO) Framework is a conceptual, scientifically validated (Evidence Based Management) structure that managers can use for deciding what to focus on in order to improve organizational performance and make it sustainable.

What two things influence an individual’s phenotype?

An organism’s phenotype results from two basic factors: the expression of an organism’s genetic code, or its genotype, and the influence of environmental factors. Both factors may interact, further affecting phenotype.

Why are phenotypes important?

Phenotype matching is important, because it allows differential behavior toward previously unmet animals. Because phenotype matching nearly always employs information learned from relatives for discriminations, these behavioral decisions are consistent with kin selection.

Can people have the same phenotype?

The answer is yes, two different genotypes can result in the same phenotype. Remember, the recessive phenotype will be expressed only when the dominant allele is absent, or when an individual is homozygous recessive (tt) (Figure below).

Which race is the most genetically diverse?

Pygmies and the bushmen of Africa are the most genetically diverse people on Earth. For some genetic traits they have as many as 17 variations, where the rest of the peoples of Earth have only two or three.