What is the clinical significance of ASO test?

Positive ASO test confirms past infection; thus it’s useful to support the diagnosis of the poststreptococcal illness when it’s suspected, like poststreptococcal glomerulonephritis, pediatric autoimmune neuropsychiatric disorders associated with streptococcus (PANDAS), and rheumatic fever.

What is ASO titer?

Definition. Antistreptolysin O (ASO) titer is a blood test to measure antibodies against streptolysin O, a substance produced by group A streptococcus bacteria. Antibodies are proteins our bodies produce when they detect harmful substances, such as bacteria.

What is the principle of ASO test?

PRINCIPLE OF THE TEST ASO test method is based on an immunologic reaction between streptococcal exotoxins bound to biologically inert latex particles and streptococcal antibodies in the test sample. Visible agglutination occurs when increased antibody level, are present in the test specimen.

Is fasting required for ASO test?

This ASO Blood Test is a sensitive test for recent streptococcal infection. Preparation: Fasting for 6 hours required. Test Results: 1-2 days.

What if ASO level is high?

ASO antibodies will remain detectable in your blood for several months after an infection. If you have elevated levels of ASO antibodies, it means that you have probably had a recent strep infection. If your levels are taken again later and are higher, it also means you’ve probably had a recent strep infection.

What is the treatment for ASO positive?

The main function of streptolysin O is to cause hemolysis (the breaking open of red blood cells)—in particular, beta-hemolysis. Increased levels of ASO titre in the blood could cause damage to the heart and joints. In most cases, penicillin is used to treat patients with increased levels of ASO titre.

What happens if ASO positive?

How do you treat ASO positive?

How do I lower my ASO levels?

Corticosteroids and certain antibiotics may reduce ASO antibody levels. This may make it difficult for your doctor to confirm your diagnosis. Tell your doctor about all the medications you’re taking. Be sure to include both prescription and over-the-counter drugs.

Can ASO be cured?

In most cases, penicillin is used to treat patients with increased levels of ASO titre.