What happens if aminophylline is infused too rapidly?

Too rapid intravenous administration may result in the following symptoms: anxiety, headache, nausea and vomiting, severe hypotension, dizziness, faintness, lightheadedness, palpitations, syncope, precordial pain, flushing, profound bradycardia, premature ventricular contractions, cardiac arrest.

How fast can you push aminophylline?

Loading doses should be administered over 30 minutes at a rate not to exceed 21 mg/hr and should be calculated using ideal body weight.

Why is aminophylline given slowly?

Intravenous Aminophylline must be administered very slowly to prevent dangerous central nervous system and cardiovascular side-effects due to direct stimulating effect of Aminophylline.

When is iv aminophylline used?

Aminophylline injection is used together with other medicines to treat the acute symptoms of asthma, bronchitis, emphysema, and other lung diseases in a hospital setting. Aminophylline belongs to a group of medicines known as bronchodilators.

Does aminophylline cause bradycardia?

Aminophylline frequently caused bradycardia in intact dogs and positive chrono- and inotropic effects in isolated atria. However, pentoxifylline usually produced only tachycardia in the donor dog and positive chrono- and inotropic effects on the isolated atrium.

Does aminophylline lower blood pressure?

6. Does Aminophylline lower BP? No, Aminophylline or any of its combinations do not affect blood pressure. Aminophylline contains theophylline, which increases the heart rate and systolic blood pressure.

How do you give IV aminophylline?

(a) A loading dose of 6mg/kg body weight of aminophylline may be given by slow intravenous injection at a rate not exceeding 25mg/min. (b) Depending on the status of the patient, the maintenance dose for the next 12 hours may be considered as follows: Children aged 6 months to 9 years: 1 .

Does aminophylline increase blood pressure?

No, Aminophylline or any of its combinations do not affect blood pressure. Aminophylline contains theophylline, which increases the heart rate and systolic blood pressure.

What is a common side effect of aminophylline?

vomiting. increased or rapid heart rate. irregular heartbeat. seizures.

Is aminophylline short or long acting?

Short-acting last for 4 to 6 hours. These include Aminophylline, Choledyl, Oxtryphylline. Long-acting last for 12 hours.

Does aminophylline cause hypotension?

Both compounds produced a dose-dependent hypotension. Aminophylline frequently caused bradycardia in intact dogs and positive chrono- and inotropic effects in isolated atria.

How do you administer aminophylline?

Aminophylline Injection is administered by slow intravenous injection or diluted and administered by intravenous infusion. The solution contains no bacteriostat or antimicrobial agent and is intended for use only as a single-dose injection. When smaller doses are required the unused portion should be discarded.

How do you dilute IV aminophylline?

Dilute 1000mg aminophylline in 1000ml sodium chloride 0.9% or 1000ml glucose 5%, to make a concentration of 1mg per 1mL, and administer as a continuous intravenous infusion. Maintenance doses should be administered immediately after the loading dose.

Can aminophylline cause hypotension?