Who first discovered the effects of aspirin?

In 1897, Felix Hoffman, a German chemist working for the Bayer company, was able to modify salicylic acid to create acetylsalicylic acid, which was named aspirin (Fig.

Who discovered aspirin and What plant is it from?

1830: Salicin is also found in the meadowsweet flower by Swiss pharmacist Johann Pagenstecher and later by German researcher Karl Jacob Löwig. 1876: The first rigorous clinical trial of salicin finds that it induces remission of fever and joint inflammation in patients with rheumatism (Lancet 1876;1:383).

How is acetylsalicylic acid made in industry?

The production process involves the reaction of Salicylic acid and acetic anhydride in glass lined vessels. The liquid produced is pumped to a crystallizer, where it is cooled down to start the crystallization to Aspirin.

Where did aspirin originally come from?

Weeping willow to salicylic acid. Willow bark has been used as a traditional medicine for more than 3500 years. Unknown to the ancient Sumerians and Egyptians who made use of it, the active agent within willow bark was salicin, which would later form the basis of the discovery of aspirin (Fig 1).

Why is aspirin called the miracle drug?

Since its introduction into the market in 1899, aspirin has veritably proven to be a miracle drug with extensive use for its analgesic and anti-inflammatory effects and subsequently for its cardioprotective effects.

Who invented ibuprofen?

Chemist John Nicholson and pharmacologist Stewart Adams developed ibuprofen during the 1950s and 1960s at Boots Pure Drug Co. in England. Today, ibuprofen is a popular first-line treatment for safely reducing pain, fever and inflammation, and it is available in more than 80 countries.

What company commercialized aspirin?

On this day in 1897, a German chemist named Felix Hoffman created a chemically pure and stable form of salicylic acid–otherwise known as the active ingredient in aspirin, the drug which came to be produced by Bayer, the company he worked for. It introduced a new world of pain relief, one that relied on an age-old cure.

Where is aspirin manufactured?

Most of the North American supply of aspirin, for example, comes from China, which produces about 120 billion tablets per year. Other widely used drugs, such as omeprazole and simvastatin often come from Puerto Rico and India. Maybe this is no big deal.

How is salicylic acid produced commercially?

Salicylic acid is produced commercially via the Kolbe-Schmitt process. Here phenol and sodium hydroxide are reacted to make sodium phenoxide. The phenoxide is contacted with CO2 to form sodium salicylate. The salicylate is acidified to give salicylic acid.

What drug is wonder drug?

Ivermectin, ‘Wonder drug’ from Japan: the human use perspective.