What is hilar lymphadenopathy sarcoidosis?

Sarcoidosis is a multisystemic disorder of unknown etiology that most commonly affects adults between 20 and 40 years of age. Patients with sarcoidosis frequently present with bilateral hilar lymphadenopathy and pulmonary infiltration, and often with ocular and skin lesions.

Can sarcoidosis metastasize?

Sarcoidosis can mimic metastasis, predominately in mediastinum, representing a diagnostic pitfall. Therefore, biopsies must always be performed to exclude the metastatic spread before initiation of any antineoplastic treatment.

Which lymph nodes swell with sarcoidosis?

Sarcoidosis can cause swollen cheeks and dry mouth. It also can cause swollen lymph nodes, sometimes occurring within the chest, but also may occur under the chin, in the armpit area or in the groin.

Can you have sarcoidosis and cancer at the same time?

While rare, the coexistence of pulmonary sarcoidosis and lung cancer has been reported [5,6,7,8]. The relationship between sarcoidosis and cancer is unclear, although three hypotheses have been suggested. First, persistent sarcoidosis may increase the risk of development of cancer [12,13,14].

What are the final stages of sarcoidosis?

Stage I: Lymphadenopathy (enlarged lymph nodes) Stage II: Enlarged lymph nodes with shadows on chest X-ray due to lung infiltrates or granulomas. Stage III: Chest X-ray shows lung infiltrates as shadows, which is a progressive condition. Stage IV (Endstage): Pulmonary fibrosis or scar-like tissue found on a chest X-ray …

Can sarcoidosis turn into lymphoma?

Coexistence of sarcoidosis and lymphoma has been reported previously. In fact, patients with sarcoidosis are up to 11 times more likely to develop lymphoma.

Can you treat sarcoidosis with chemotherapy?

Cyclophosphamide (brand names, Cytoxan and Neosar) is a chemotherapy approved to treat a number of cancers, and may be used to treat select sarcoidosis patients because of its ability to suppress the immune system.

How often does sarcoidosis turn into cancer?

Sarcoidosis is associated with an increased risk for cancer development in several organs like lung, liver, stomach or for melanoma and lymphoma. Sarcoid-like reactions can be found in 13.8% of patients with Hodgkin-disease, 7.3% with non Hodgkin lymphoma and 4.4% of cases with carcinomas (4,5).

Can sarcoidosis look like lung cancer?

It is well recognized that sarcoidosis can mimic infectious, malignant, and granulomatous conditions and may predispose patients to the development of lung cancer [12]. Here, we report a case with a high initial index of suspicion for lung malignancy in terms of clinical, lung imaging, and endoscopic findings.