What is the most common histologic finding in epilepsy?
What is the most common histologic finding in epilepsy?
Conclusions. In patients with drug-resistant focal epilepsy requiring surgery, hippocampal sclerosis was the most common histopathological diagnosis among adults, and focal cortical dysplasia was the most common diagnosis among children.
What is the pathology of epilepsy?
epilepsy, chronic neurological disorder characterized by sudden and recurrent seizures which are caused by an absence or excess of signaling of nerve cells in the brain.
What is the Epileptogenic area?
The epileptogenic zone is defined as the region of the brain from which the patient’s habitual seizures arise.
What nervous tissue cells are involved in epilepsy?
Microglia and astrocytes are the main inflammatory cells in the nervous system. Glia-mediated inflammation induced by various brain insults can promote seizures and epileptogenesis (Figure 2), especially when the inflammation is difficult to control (Eyo et al., 2017).
What is the anatomy of epilepsy?
Non-epileptic seizure is short-lived while epilepsy is a neurological condition characterized by two or more provoked seizures. The hippocampus, amygdala, frontal cortex, temporal cortex, and olfactory cortex are the common areas involved in seizures.
What happens to neurons during epilepsy?
In epilepsy, the normal pattern of neuronal activity becomes disturbed, causing strange sensations, emotions, and behavior, or sometimes convulsions, muscle spasms, and loss of consciousness. During a seizure, neurons may fire as many as 500 times a second, much faster than the normal rate of about 80 times a second.
What is the difference between epilepsy and seizure?
A seizure is a single occurrence, whereas epilepsy is a neurological condition characterized by two or more unprovoked seizures.
What is Epileptogenic focus?
The epileptic focus is an area of the cerebral cortex that is essential for the generation of seizures. It is the region where epileptic seizures begin, or the site with the most ictal activity, also known as the epileptogenic zone.
