What is similar to Reye syndrome?

As Reye’s syndrome is so rare, other conditions that can cause similar symptoms need to be ruled out. These include: meningitis – inflammation of the protective membranes surrounding the brain and spinal cord. encephalitis – inflammation of the brain.

What is associated with Reye’s syndrome?

Reye’s syndrome seems to be triggered by using aspirin to treat a viral illness or infection — particularly flu (influenza) and chickenpox — in children and teenagers who have an underlying fatty acid oxidation disorder.

When does Reye’s syndrome occur?

Reye syndrome usually affects children between ages 4 and 12, but it can occur at any age. Symptoms occur very suddenly. If Reye syndrome is diagnosed and treated early, many children recover fully. But if not treated quickly, Reye syndrome can cause a child to go into a coma, lead to brain damage, or cause death.

What is responsible for the disturbed liver function in Reye syndrome?

Researchers suggest that the primary underlying defect in Reye syndrome is abnormal functioning of mitochondria with reduced activities of liver (hepatic) mitochondrial enzymes (e.g., ornithine transcarbamylase [OTC], carbamyl phosphate synthetase [CPS], pyruvate dehydrogenase [PDH]).

What is Reye’s syndrome pathophysiology?

The pathophysiology of Reye’s syndrome is thought to involve mitochondrial injury, which inhibits oxidative phosphorylation and fatty-acid beta-oxidation. High concentrations of ammonia may accumulate due to the decrease in the activity of the mitochondria.

What is viral baby syndrome?

The viral syndrome is a viral infection that is caused by the virus or viruses that affects the mostly respiratory tract. But it can affect any body part. Doctors use terminology “Viral Syndrome”, when your child’s infection looks like it is caused by virus.

How is Reye syndrome diagnosed?

Lumbar puncture (spinal tap) There’s no specific test for Reye’s syndrome. Instead, screening for Reye’s syndrome usually begins with blood and urine tests as well as testing for fatty acid oxidation disorders and other metabolic disorders.

Why does Reye syndrome cause hypoglycemia?

Hepatic gluconeogenesis from pyruvate as evaluated in liver biopsies was markedly depressed in Reye syndrome as compared to animal controls. These results indicate that the hypoglycemia of Reye syndrome is secondary to decreased hepatic glucose production.

Is ibuprofen A aspirin?

Aspirin and ibuprofen contain different active ingredients — whereas aspirin is made with salicylic acid, ibuprofen is made with propionic acid. However, both aspirin and ibuprofen can be used to treat pain caused by inflammation or injury, headaches, fevers, arthritis, and menstrual cramps.

Why aspirin is 81 mg?

Aspirin dosing is rooted in this history. The standard adult aspirin dose was 5 gr, or 325 mg in metric, the dose still used today for analgesia. Low-dose aspirin was one quarter of the standard dose, 1.25 grains, which converted to 81 mg.