Can Lantus be dosed twice daily?

Because of its long duration of action insulin glargine is usually prescribed once daily. However, several reports have shown that the administration of insulin glargine once daily is not enough to achieve adequate glucose control in some patients requiring a twice daily dosing [2], [3], [4], [5], [6], [7], [8], [9].

Can long-acting insulin be given twice a day?

Research has shown that twice-daily dosing with insulin glargine significantly improved blood glucose control in 50 patients with uncontrolled type 2 diabetes. The average daily dose of insulin glargine increased from 53 units/day to 78 units/day, and a higher dose of short-acting insulin was needed at mealtimes.

When should I take insulin twice daily?

What is a twice daily insulin regimen? On a twice daily insulin regimen, you will inject a mixture of a shorter acting insulin and intermediate acting insulin at two different times of the day, before breakfast and before dinner. The shorter acting may be either short acting insulin or a rapid acting insulin.

How much Lantus can you take in a day?

Your initial dose of Lantus will likely be 0.2 units of Lantus for every kilogram (kg)* of body weight. The maximum starting dose of Lantus is 10 units per day.

What happens if you take Lantus twice?

If you double a dose, this may cause low blood sugar levels. High blood sugar levels over a period of time can lead to too much acid in the blood (diabetic ketoacidosis). Contact your doctor immediately if your blood sugar level is very high or you experience any of the following symptoms.

Is 50 units of Lantus too much?

It is possible that the “maximum” of 50 units is derived from the technical limitations of the 1/2 mL syringe. The Lantus SoloStar disposable pen has a maximum “dial-able” dose of 80 units. Aside from this technical maximum, there is no mention of a maximum dose in the package insert.

Is 30 units of Lantus too much?

There is no maximum dose of glargine per se, although at doses >100 units, I usually prescribe this agent b.i.d. In addition, we are finding that in some patients, Lantus seems to last only 12-18 hours, so that splitting the dose to 80 units in the morning and 30 units at bedtime would likely improve his morning/ …

What is the peak time for Lantus?

Long-Acting Insulin This insulin group has an onset of action between 1-2 hours and a peak action time that varies between 6-20 hours. Note that Lantus® does not peak, but provides a steady level of insulin throughout the duration time. Total duration of action is anywhere between 20-36 hours.

How long does it take for Lantus to lower blood sugar?

It takes about 90 minutes to begin working after injection, and it stops working after about 24 hours. After injection, insulin glargine is released slowly and constantly into the bloodstream.

Why is Lantus given at bedtime?

Abstract. Aims/hypothesis: Insulin glargine is a long-acting human insulin analog often administered at bedtime to patients with type 2 diabetes. It reduces fasting blood glucose levels more efficiently and with less nocturnal hypoglycemic events compared with human neutral protamine Hagedorn (NPH) insulin.

Do you still give Lantus if blood sugar is low?

You should not take Lantus during an episode of low blood sugar level. This is because Lantus can cause and also worsen this condition.

Is it better to take Lantus at night or in the morning?

Lantus can be used any time of day but at the same time every day. You should pick a time of the day that will be convenient and when it will be easiest to remember.

Is 15 units of Lantus a lot?

For people with type 2 diabetes who aren’t currently taking insulin, the recommended starting dosage of Lantus is 0.2 units/kg or 10 units once per day. The maximum starting dosage of Lantus is 10 units per day.

Should I take my Lantus if my blood sugar is low?

How many units of insulin should I take if my blood sugar is 500?

Thus: 500 ÷ total daily dose = the number of grams of carbs covered by 1 unit of rapid-acting insulin. If your total daily dose was 50, this would give you the following calculation: 500 ÷ 50 = 10. This would mean that 10 grams of carbs would require 1 unit of insulin, giving you the ratio of 1:10.

What blood sugar is too low for Lantus?

If you have symptoms of hypoglycemia, check your blood sugar level right away. If it’s below 70 mg/dL, the American Diabetes Association recommends that you follow the “15–15 rule.” To do this, you should eat at least 15 grams (g) of fast-acting carbohydrates. Wait 15 minutes, then check your blood sugar level again.

How much does each unit of Lantus lower blood sugar?

Generally, to correct a high blood sugar, one unit of insulin is needed to drop the blood glucose by 50 mg/dl. This drop in blood sugar can range from 30-100 mg/dl or more, depending on individual insulin sensitivities, and other circumstances.