What is carcinoma ex pleomorphic adenoma?

Carcinoma ex pleomorphic adenoma (CXPA) is a carcinoma arising from a primary or recurrent benign pleomorphic adenoma. It often poses a diagnostic challenge to clinicians and pathologists. The entity is difficult to diagnose preoperatively. Pathological assessment is the gold standard for making the diagnosis.

Is pleomorphic adenoma fatal?

Pleomorphic adenoma (PA) is the commonest benign neoplasm affecting the parotid gland most often (> 75%), followed by the submandibular gland (13%), then the palate (9%). Metastasising pleomorphic adenoma (MPA) is extremely rare. The effects can be severe and a reported 40% of MPA patients die with disease.

What percentage of pleomorphic adenomas become malignant?

Pleomorphic adenomas harbor a small risk of malignant transformation. The malignant potential is proportional to the time the lesion is in situ (1.5% in the first five years, 9.5% after 15 years). Therefore, excision is warranted in almost all cases.

Is pleomorphic adenoma curable?

There are many types of benign salivary gland tumors, with names such as pleomorphic adenoma, oncocytomas, and Warthin tumors. Benign tumors are almost always cured by surgery.

Can pleomorphic adenoma spread?

Although pleomorphic adenoma is a benign tumor, it can metastasize especially when the excision was incomplete.

Can pleomorphic adenoma metastasis?

Although pleomorphic adenoma is a benign tumor, it can metastasize especially when the excision was incomplete. The most frequent primary site of a metastasizing pleomorphic adenoma is the parotid gland, where complete excision is difficult due to critical anatomical problems such as the presence of the facial nerve.

Is pleomorphic adenoma painful?

The lesion occurs most often in the parotid gland but may also arise in the submandibular, sublingual and minor salivary glands. Pleomorphic adenoma typically presents as a slow-growing, painless, firm mass and is only occasionally associated with facial palsy or pain.

Does a pleomorphic adenoma cause pain?

What is the recovery time for a parotidectomy?

The skin may get a little yellowish because the fluid under the surface is being absorbed and cause this color change. The skin color will return to normal in the following two weeks. May return to work anywhere between 10-14 days after surgery. May return to exercise in 3-4 weeks.