Which treatment is best for pemphigus vulgaris?
Which treatment is best for pemphigus vulgaris?
Systemic corticosteroids remain the gold standard treatment for pemphigus vulgaris. Azathioprine and mycophenolate mofetil are the first line of steroid-sparing treatment. Rituximab is extremely effective in recalcitrant pemphigus, when other treatments fail to control the disease.
How do you treat pemphigus wounds?
The primary goal of treatment is to induce durable remission, decrease blister formation, prevent infections and promote healing of blisters and erosions. The mainstay of treatment for pemphigus is systemic corticosteroids combined with an adjuvant immunosuppressant and wound care.
How do you treat pemphigus vulgaris naturally?
Self-help
- Avoiding activities that could cause the skin to become damaged, such as contact sports.
- Using a soft toothbrush.
- Avoid crisp, hard, hot or spicy foods.
- Taking painkillers, particularly prior to eating or brushing the teeth.
- Maintaining good oral and skin hygiene.
What medication is used to treat pemphigus?
Either azathioprine or mycophenalate mofetil is often used to treat pemphigus. These can stop the body from creating new blisters. Biologics: This is a newer treatment option. One biologic, rituximab, seems promising.
How long does rituximab take to work for pemphigus?
Our study demonstrated the efficacy of rituximab for severe pemphigus; 86% of patients were in complete remission 3 months after receiving four weekly infusions of rituximab. After a 34-month follow-up period, 18 patients were free of disease, and 8 of these patients were not receiving any systemic therapy.
What is penicillamine used for?
Descriptions. Penicillamine is used in the treatment of medical problems such as Wilson’s disease (too much copper in the body) and rheumatoid arthritis. Also, it is used to prevent kidney stones. Penicillamine may also be used for other conditions as determined by your doctor.
Can rituximab cure pemphigus vulgaris?
Rituximab was effective in treating pemphigus vulgaris, was significantly better than conventional treatment, decreased the need for additional steroids and other immunosuppressants and induced prolonged remission. Rituximab was more effective when given early in the disease process.
