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What has Urolithin A?

What has Urolithin A?

Dietary sources of urolithin A So far, research has found that pomegranate, strawberries, blackberries, camu-camu, walnuts, chestnuts, pistachios, pecans, brewed tea, and oaken barrel-aged wines and spirits contain ellagic acid and/or ellagitannins [4, 5].

What gut bacteria produces Urolithin A?

Urolithin A (UA) is produced by gut microflora from foods rich in ellagitannins. UA has been shown to improve mitochondrial health preclinically and in humans. Not everyone has a microbiome capable of producing UA, making supplementation with UA an appealing strategy.

What is Urolithin a supplement?

Urolithin A (UA) Is a Gut Microbiome-Derived Compound with Health Benefits for Aging and Diseases. Several dietary products contain the natural polyphenols ellagitannins (ETs) and ellagic acid (EA). Upon ingestion of such foods, ETs and EA are metabolized into UA by the microflora in the large intestine.

Where does Urolithin a come from?

Urolithin A (UA) is a natural compound produced by gut bacteria from ingested ellagitannins (ETs) and ellagic acid (EA), complex polyphenols abundant in foods such as pomegranate, berries, and nuts.

Does urolithin A work?

Available from the diet and more effectively, from dietary supplements, urolithin A has been shown to promote mitochondrial health and muscle endurance. It does this by improving mitochondrial activity, specifically by activating the process of mitophagy.

How much urolithin A is in pomegranate?

269.9
Dietary sources

Dietary source Ellagic Acid
Boysenberries 70
Cloudberries 315.1
Pomegranate 269.9
Raspberries 270

Is urolithin A probiotic?

The identification of a bifidobacterial strain producing urolithins A and B opens the possibility for its application as probiotic in functional foods and in the development of nutraceuticals.

Does pomegranate juice contain urolithin A?

The most abundant type of polyphenols in pomegranate juice are ellagitannins that are hydrolyzable tannins releasing ellagic acid on hydrolysis (Gil et al. 2000) and form urolithins such as urolithin A following metabolism by gut flora (FIGURE 10.1).

Is urolithin A safe?

The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans. Nat Metab. 2019 Jun;1(6):595-603.

Is urolithin A in pomegranate extract?

Chemical structures of punicalagin isomers, the major ellagitannins present in pomegranate juice and its metabolites, dimethylellagic acid glucuronide, ellagic acid, and urolithins A and B.

What is Mito pure?

What is Mitopure? Mitopureā„¢ is a proprietary and highly pure form of Urolithin A. It helps our bodies counter age-associated cellular decline by revitalizing the power generators inside of our cells; i.e. our mitochondria.

Does pomegranate juice have urolithin A?

How much urolithin A is in a pomegranate?

Does Urolithin a work?

The findings from this exploratory work suggest that urolithin A is a promising approach to counteracting age-associated muscle decline. However, future work is needed to confirm the beneficial role of urolithin A supplementation in healthy aging.

Does pomegranate juice contain Urolithin A?

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