What causes Hypocellular bone marrow?

Abstract. Pancytopenia with hypocellular bone marrow most often is caused by idiopathic aplastic anemia, but can be caused by inherited bone marrow failure syndromes, drugs, infections, nutritional deficiencies, and rheumatologic disease.

What is Hypercellular bone marrow with Trilineage hematopoiesis?

Myeloid cells are involved in trilineage hematopoiesis. This term refers to the normal production by your bone marrow of three blood cell lines: red blood cells, certain white blood cells, and platelets. Lymphoid cells create a separate white blood cell line leading to T cells and B cells.

What infections can cause pancytopenia?

If you have pancytopenia, you have a combination of three different blood diseases: anemia, or low level of red blood cells. leukopenia, or low level of white blood cells….viral infections, such as:

• Epstein-Barr virus, which causes mononucleosis.
• cytomegalovirus.
• HIV.
• hepatitis.
• malaria.
• sepsis (a blood infection)

Is pancytopenia a form of leukemia?

Pancytopenia is the reduction in the number of all 3 major cellular elements of blood and leads to anemia, leukopenia, and thrombocytopenia. A wide variety of etiologies result in pancytopenia including leukemia, aplastic anemia, and megaloblastic anemia.

What can cause Hypercellular bone marrow?

Hypercellular marrow can occur when there is increased production in one or more cell lineages or there is an increased number of neoplastic cells (acute leukemia, multiple myeloma, histiocytic sarcoma, etc.).

What bacteria causes pancytopenia?

Pancytopenia causes and risk factors

• Epstein-Barr virus, which causes mononucleosis.
• cytomegalovirus.
• HIV.
• hepatitis.
• malaria.
• sepsis (a blood infection)

Is pancytopenia part of multiple myeloma?

Pancytopenia in multiple myeloma may be attributed to several reasons. Most often it is due to the plasma cell proliferation replacing normal haematopoietic cells. Other causes include fas-ligand mediated apoptosis or cytokine-mediated bone marrow failure or even renal failure induced erythropoietin deficiency [5].