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Can phenobarbital cause bradycardia?

Can phenobarbital cause bradycardia?

Nervous system: Agitation, confusion, hyperkinesia, ataxia, CNS depression, nightmares, nervousness, psychiatric disturbance, hallucinations, insomnia, anxiety, dizziness, thinking abnormality. Respiratory system: Hypoventilation, apnea. Cardiovascular system: Bradycardia, hypotension, syncope.

Does phenobarbital decrease heart rate?

With hypnotic doses, respiratory depression produced by Phenobarbital is similar to that which occurs during physiologic sleep with slight decrease in blood pressure and heart rate.

What can I monitor with phenobarbital?

The following drugs are reported to have clinically significant interactions with phenobarbital:

  • Oral blood-thinning medications like warfarin.
  • Antidepressants and tricyclics, including MAO inhibitor antidepressants.
  • Central nervous system depressants, sedatives, hypnotics and tranquilizers.
  • Antihistamines.
  • Alcohol.

What are side effects of phenobarbital?

Phenobarbital may cause side effects. Call your doctor if any of the following symptoms are severe or do not go away:

  • drowsiness.
  • headache.
  • dizziness.
  • excitement or increased activity (especially in children)
  • nausea.
  • vomiting.

Does phenytoin cause bradycardia?

Phenytoin is an anticonvulsant which is also a Class IB antiarrhythmic. Its common adverse drug reactions (ADRs) include gastrointestinal symptoms, psychiatric disorders, gingival hyperplasia, and rash. Bradycardia and hypotension following intravenous (IV) phenytoin are rare ADRs.

What are the side effects of taking phenobarbital?

Does phenobarbital affect blood pressure?

At anticonvulsant dosage, phenobarbital sodium decreased mean arterial blood pressure transiently during steady state and significantly reduced total cerebral blood flow during phenylephrine-induced hypertension without reducing mean arterial blood pressure.

Does phenobarbital cause shortness of breath?

Phenobarbital side effects weak or shallow breathing; unusual pain anywhere in your body (especially in the neck, shoulder, or arms); a red blood cell disorder–pale skin, muscle weakness, diarrhea, weight loss, rapid heart rate, tongue swelling, numbness or tingling in your hands or feet, feeling short of breath; or.

What are the side effects of phenobarbital?

When should you monitor phenobarbital levels?

Scheduled monitoring of phenobarbital levels has increased its safety and efficacy. We will usually recommend checking a phenobarbital level 4 weeks after reaching a therapeutic dose and then every 4-12 months thereafter.

How long do phenobarbital side effects last?

Common short-term side effects of phenobarbital are mild sedation and some incoordination. Longer term side effects may be increased appetite, and, occasionally, increased thirst and urination. After 7-10 days, these effects wear off and your pet should appear normal again.

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